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Reconstruction of proteomic profiles for biomarker discovery
This thesis has been prepared at the CEA Léti, Minatec Campus, (Grenoble, France) and the IMS (Bordeaux, France) in the field of information and signal processing of... -
Approche métabonomique pour l'obtention des signatures urinaires des différen...
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Contribution to the thermal treatments of wood up to 300°C : Chemical transfo...
Un bois traité à une température inférieure à 300°C et sous atmosphère inerte voit sa composition chimique modifiée. Ceci a pour effet de changer sa couleur, de le... -
Mass spectrometry and ion mobility developments to the study of supramolecula...
The aim of this thesis was the development of different supramolecular approaches, like MS and IM-MS, to characterize precisely protein/ligand interaction and to... -
Oligonucleotide analysis by fast electron bombardment
This work aims to study oligonucleotides and mononucleotides by new fragmentation techniques such as EDD (electron-detachment-dissociation) and EID... -
Conformational studies of peptides and proteins by ion mobility-mass spectrom...
This work deals with the conformational studies of biomolecules in gas phase. The gas phase allows observing the intrinsic factors that stabilize the structure.The... -
Synthesis and characterization of nanoclusters stabilized by thiolates
My research works concerns the synthesis and characterization of nanoclusters stabilized by thiolates(SG), particularly the gold and silver nanoclusters. The study of... -
Study of the degradation of pesticides by direct photolysis- structural ident...
date de rédaction: fin juin -
Applications of MALDI-TOF mass spectrometry to the bacteriology and to the di...
The aim of this work was to validate and optimize MALDI-TOF mass spectrometry for the identification and classification of a set of pathogens or opportunistic... -
La thermo-ionisation en spectrométrie de masse isotopique
Document de synthèse rassemblant les informations disponibles sur les différentes méthodes de dépôts d'échantillons pour analyse isotopique par spectrométrie de masse... -
Absolute and targeted quantification of proteins and peptides by liquid chrom...
Both in clinical and environmental research, protein biomarkers are of growing interest. Although immunoassays are the gold standard for their quantification, recent... -
Evaluation of the fungal risk in shellfish farming areas: toxic substances fr...
This work is devoted to the chemical study of peptaïbols produced by endemic Trichoderma strains in the Loire-Atlantique shellfish farming areas. The adopted strategy... -
A mini review: proteomic analysis, a post-genomic approach
International audience -
A chromatographic procedure for semi-quantitative evaluation of caseinphospho...
International audience -
Composition of cholesterol and its precursors in ovine milk
International audience -
Study and development of a mass spectrometer and energy : modeling and optimi...
The objective of my work was to develop, implement and test a neutral mass spectrometer to study planetary exospheres, NIMEIS (Ion and Neutral Mass and Energy Imaging... -
STRUCTURAL AND FUNCTIONAL ANALYSIS OF NEUTROPHIL NADPH OXIDASE FROM NEUTROPHI...
NADPH oxidase (NOX) is a multienzymatic complex found in many cellular types, responsible for reactive oxygen species (ROS) production. The neutrophilic NOX is... -
Production and characterization of protonated molecular clusters containing a...
Nanoscale characterization of irradiation in biomolecular systems requires observation of novel features which are now achievable with the recent technical progress....
