Integration of micro sensors within an embedded system is a challenging task in terms of commercial application and deals with many fields of research. This report compiles a novel methodology of multi-sensor integration, from the design to the experimental evaluation. The reported MEMS gas sensor is made from a resistive micro-wire. It is designed to the sensing of temperature, pressure and humidity of a gaseous sample, at the same time, in using only a single sensing part as well as a single conditioning principle – which is by itself a new feature arbitrarily called "total integration". The physical principle involved here is heat-diffusion, where heat is produced by Joule effect within the resistive sensing part, sinking through the gaseous sample. The key is that the transient response of such a sensor enables the reading of both the sample thermal conductivity and heat capacity, depending on both humidity and pressure at a given temperature, the later being only depending upon the initial response of the sensor transient response.