7 datasets found

Recently, Genome-Wide Association Studies (GWAS) have led to the discovery of numerous genetic polymorphisms involved in complex human diseases. However, these...

MicroRNAs, as short endogenous non-coding RNAs, play an important role in post-transcriptional gene silencing. Altered expression of these miRNAs can contribute to the...

Idiopathic Pulmonary Fibrosis (IPF) is a fibroproliferative disease with poor prognosis and for which no effective treatment exists. The mechanisms of this disease...

Androgens signaling through the androgen receptor (AR) is critical for normal prostate development and function, as well as prostate cancer initiation and progression....

Neuroblastoma, an embryonal tumour of neuro‐ectodermal origin, stands up with brain tumours as the most worrying cancer of paediatric oncology. The huge heterogeneity...

Sarcomas are malignant soft tissue tumors, accounting for 1% of adult tumors and 8% of all pediatric malignancies. Sarcomas are rare, and display a variety of...

Kidney cancer is a major public health problem. Early diagnosis improves the chances of survival. The diagnosis is mainly based on the imaging tests such as...