Biomechanical characterization of the ascending thoracic aortic aneurysms

Epidemiology of aortic aneurysms is a major public health issue that affects a significant proportion of the population in industrialized countries and can cause the death of the patient in case of rupture of the aneurysm.Currently the only criteria for surgery are based on the morphology of the aneurysm, and there are problems to accurately assess the risk of rupture for each patient.The aim of this thesis was to develop a method to identify the mechanical properties of the arterial wall in a personalized way to refine the criteria for surgery.Inflation tests, full-field measurements and a methodology developed were used in order to quantify experimentally the stress distribution of aneurysms. It was possible to highlight the appearance of localized weakening in the wall which will let us predict the location of the rupture on the aneurysm. Then a method was developed to identify the mechanical properties of the aortic tissue. It was possible to highlight the heterogeneity of arterial tissue and locate the places where the rupture of the tissue may occur.The identification of the aneurysm’s mechanical properties from experimental data will improved arterial numerical models used today. In addition, the methodology developed for the analysis of the rupture of aneurysms during this thesis opens the door to a step that aims to develop the in vivo mechanical characterization by the use of medical imaging. The ultimate goal will be to assess the risk of rupture of the aneurysm of each patient in a noninvasive manner.

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Source https://theses.hal.science/tel-00994236
Author Romo Marquez, Aaron
Maintainer CCSD
Last Updated May 5, 2026, 10:39 (UTC)
Created May 5, 2026, 10:39 (UTC)
Identifier NNT: 2014EMSE0727
Language fr
Rights https://about.hal.science/hal-authorisation-v1/
contributor Surfaces et Tissus Biologiques (STBio-ENSMSE) ; École des Mines de Saint-Étienne (Mines Saint-Étienne MSE) ; Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-CIS
creator Romo Marquez, Aaron
date 2014-01-13T00:00:00
harvest_object_id 466441bd-66cd-4fda-b610-3fa323f08296
harvest_source_id 3374d638-d20b-4672-ba96-a23232d55657
harvest_source_title test moissonnage SELUNE
metadata_modified 2026-03-31T00:00:00
set_spec type:THESE