To develop a beam hodoscope in hadrontherapy, able to localize the beam position and to get a time tagging with a accuracy of ~ 1ns at a count rate of 100 000 000 HZ, we have studied and designed read-out ASICs' (Application Specific Intergrated Circuits) to be associated with multi-anode photomultiplier. One of 16-channel front-end ASIC in 0,35 µm AMS BICMOS process ahs been designed, fabraicated and tested. Each channel consists to a current coveyor (with two current outputs) as an input stage, and two separat output stages wich are a current comparator and a charge-sensitive amplifier (CSA) respectively. It performs both signal-event detection and signal charge quantification. The design work includes optimization of circuit performances such as input dynamic range, power dissipation; speed and noise. The circuit has also ben incorporated in a test system and its opration has been verified by beam experimentation. On the other hand, we have also designed another ASIC in a 0.35 µm AMS CMOS process. Itn is based on an analog DLL (Delay Locked Loop) with implementation of the TOF (Time Of Flight) measuring method. It has a LVDS (Low Voltage Differential Signaling) clock input mode and a 5-bit Gray-code output. It operates with 200-ps timing rsolution according to test results. These studies have led us to launch a new design project: integrating the studied and validated electronic functions on a single chip.