As part of optimizing the reliability, Thales Optronics now includes systems that examine the state of its equipment. This function is performed by HUMS (Health & Usage Monitoring System). The aim of this thesis is to implement in the HUMS a program based on observations that can determine the state of the system, anticipate and alert about the excesses of operation, optimize maintenance operations and evaluate the failure risk of a mission, by combining treatment processes of operational data (collected on each equipment thanks to HUMS) and predictive data (resulting from reliability analysis and cost of maintenance, repair and standstill). Three algorithms have been developed. The first, based on hidden Markov model, allows to estimate at each time the state of the system from operational data, and thus, to detect a degraded mode of equipment (diagnostic). The second algorithm is used to propose an optimal and dynamic maintenance strategy. We want to estimate the best time to perform maintenance, according to the estimated state of equipment. This algorithm is based on a system modeling by a piecewise deterministic Markov process (noted PDMP) and the use of the principle of optimal stopping.The maintenance date is determined from operational and predictive data and the estimated state of the system (prognosis). The third algorithm determines the failure risk of a mission and compares risks following the chosen maintenance policy.This research, developed from sophisticated tools of theoretical and numerical probabilities, allows us to define a maintenance policy adapted to the state of the system, to improve maintenance strategy, the availability of equipment at the lowest cost, customer satisfaction, and reduce operating costs.