Modern circuits are more and more sensitive to environmental and technology changes. In this context, reprogrammable components like FPGAs represent an interesting technological support. Indeed, these components can adapt the physical layout of the system through a simple reconfiguration of the circuit. In this manuscript, we present a comprehensive adaptative flow to compensate the variations in reconfigurable circuits. For this, a study of all phases of digital sensor design is realized. We then propose a novel and unique characterization approach based on the electromagnetic analysis. It is particularly shown that this approach allows to get rid of measurement bias caused by direct measurement. The joint use of sensors and themethod of analysis allows a detailed and accurate characterization of technological variations of any type of FPGA. Finally, the cartography issued from the characterization phase is then used to calibrate the sensors for online use. Then, we employ these sensors for monitoring the dynamics of a system MPSOC.