In this thesis, we address three themes : columns subset selection in a matrix, the Banach-Mazur distance to the cube and the estimation of the covariance of random matrices. Although the three themes seem distant, the techniques used are similar throughout the thesis. In the first place, we generalize the restricted invertibility principle of Bougain-Tzafriri. This result allows us to extract a "large" block of linearly independent columns inside a matrix and estimate the smallest singular value of the restricted matrix. We also propose a deterministic algorithm in order to extract an almost isometric block inside a matrix i.e a submatrix whose singular values are close to 1. This result allows us to recover the best known result on the Kadison-Singer conjecture. Applications to the local theory of Banach spaces as well as to harmonic analysis are deduced. We give an estimate of the Banach-Mazur distance between a symmetric convex body in Rn and the cube of dimension n. We propose an elementary approach, based on the restricted invertibility principle, in order to improve and simplify the previous results dealing with this problem. Several studies have been devoted to approximate the covariance matrix of a random vector by its sample covariance matrix. We extend this problem to a matrix setting and we answer the question. Our result can be interpreted as a quantified law of large numbers for positive semidefinite random matrices. The estimate we obtain, applies to a large class of random matrices