This thesis for the Habilitation to Supervise Researches is based on my researches and clinical experiences in the United States, Togo, Bolivia, Vietnam and France with children and families from different backgrounds and cultures. Gathering my most significant works, it enable me to put in coherence my positions and epistemological references and to reconsider the necessary distinctions and articulations between clinical psychology, psychopathology and psychoanalysis; while continuing to question major elements relating to the psychoanalysis with children and the close link which units the particularity of the child's symptom and the universal of the subject's structure. For that, throughout this work, I stress the importance of The Symbolic Adventure which is in the heart of any subjective construction and the Clinic of the Subject and the Social Contemporary Link which ensues from it. Sigmund Freud showed us the way in the Essays of psychoanalysis by assuming very early on the specific bond linking the subject and the society. With his continuation, Jacques Lacan posed the various modalities of this tying by the symptom making hold the subject in the inevitable discontent which carries each civilization.