This thesis is about verification of timed automata, a well-established model for real time systems. The document is structured in three parts. The first part is dedicated to the determinization of timed automata, a problem which has no solution in general. We propose an approximate (over-approximation, under-approximation, mix of both) method based on the construction of a safety game. This method improves both existing approaches by combining their respective advantages. Then, we apply this determinization approach to the generation of conformance tests. In the second part, we take into account quantitative aspects of real time systems thanks to a notion of frequency of accepting states along executions of timed automata. More precisely, the frequency of a run is the proportion of time elapsed in accepting states. Then, we study the set of frequencies of runs of a timed automaton in order to decide, for example, the emptiness of threshold languages. We thus prove that the bounds of the set of frequencies are computable for two classes of timed automata. On the one hand, we prove that bounds are computable in logarithmic space by a non-deterministic procedure in one-clock timed automata. On the other hand, they can be computed in polynomial space in timed automata with several clocks, but having no cycle that forces the convergence between clocks. Finally, we study the reachability problem in networks of timed automata communicating through FIFO channels. We first consider discrete timed automata, and characterize topologies of networks for which reachability is decidable. Then, this characterization is extended to dense-time automata.
