This work considers the interaction between a flow field and the microscopic degrees of a freedom of a polymer solution. Different flow configurations were considered.Droplet pinch off, which occurs when a drop of liquid detaches from a capillary, can be strongly modified in the presence of polymers giving rise to long and slender filaments that thin slowly in time. We here study experimentaly the dynamics of necking and the conformations of polymers during the thinning of the neck. Our results show that the slow down of the thinning dynamics is the result of polymer stretching. Moreover, during the filament thinning, the polymer length distribution remains the same. This result is unexpected and led us to introduce a new method to estimate the extensionnal viscosity which represents the polymer solution resistance to stretching.In a second flow configuration, we have observed that depletion of polymer molecules near a surface occurs when a bead approaches a plate in a polymer solution.