In environment, plant performed some interactions with soil microorganisms. From these interactions, associative symbiosis involving PGPR bacteria (Plant Growth Promoting Rhizobacteria) can be considerate. Impact of phytobenefic microorganisms (Azospirillum, Pseudomonas…) leading to associatives interactions, on host plant metabolisms, still poorly understood. Zea mays L. was choose as study model because it can enter in various associatives symbiosis with Plant growth Promoting Rhizobacteria. To study effects of these microorganisms on maize, two approaches were developed thanks to metabolite profiling tools to (i) determine the impact of a single microorganism inoculation on host plant roots and shoots secondary metabolisms and (ii) evaluate physiological effect of microbial consortia including Azospirillum, Pseudomonas and Glomus species. Results of this work showed the major place of benzoxazinoids compounds (benzoxazolinone and benzoxazinone) in plant/microbe interaction and their synthesis modulation induced by inocula. Besides, our works brings to light that the metabolic answer of the plant to the interaction with microorganisms is dependent on species and bacterial strain suggesting a recognition phenomenon between both organisms
