This work is focusing on the study of the thermal Sunyaev-Zel'dovich (tSZ) effect produced by the gaz of hot electrons present in galaxy clusters. This effect consist on the interaction between the Cosmic Microwave Background (CMB) and galaxiy clusters. For this purpuse I used the data from the High Frequency Instrument (HFI) of the PLANCK satellite. This work can be divided in three main parts : (1) The study of systématics effects present in the Time Ordered Data and in the construction of the sky maps. (2) The devellopement of new components seperation methods for the tSZ effect in the context of multi-frequencies observations. (3) The physical analysis of the tSZ effect providing constraints on the galaxy clusters properties. This work allow to put some constraints on the galaxy clusters pressure profile, on the WHIM components present in the inter-clusters medium between binary system of galaxy clusters and on the detection of the tSZ power spectrum with PLANCK.