Interlocked materials are periodic paving of elementary blocks. The cohesion is insured by the boundary conditions applied on the edge of the assembly as well as the topology of the blocks and the friction between the blocks.Experiments were performed to study the mechanical response of interlocked assemblies built with cubes in alumina and osteomophic blocs in polymer. Those results have been reproduced using two numerical methods: the finite element method and the discret element method with the help of a dedicated code. Differents design parameters have been studied with numerical methods and experiments allowed us to know the response of a dammage assembly. New assemblies having a hierachical structure were proposed and tested opening new perspectives.