Logistics is a major challenge for the competitiveness of multinational enterprises. Logistics performance is largely defined in the design of the logistics network. Applied to the car maker PSA Peugeot Citroen, a decision support approach is proposed to optimize the location of investments in manufacturing capacity and the location of production volumes. This problem of international logistics network strategic planning is divided into three sub-problems of increasing complexity each giving rise to a literature review and proposals for methods of heuristics or metaheuristics optimization. These methods are validated on sets of test data as well as an industrial case study. A prototype implementation of the decision support system integrated into the company's information is presented.