In this thesis, we consider the problem of reliable data packets transmission using single-carrier signaling over frequency-selective fading channels. Our objective is to design enhanced transceivers with improved detection performance in the absence of channel state information at the transmitter by exploiting the available time-diversity in Chase combining Hybrid Automatic Repeat reQuest (HARQ) protocols. By analyzing the performance of the transmission scheme using an optimal maximum-likelihood receiver, we establish a suitable criterion for the study of system performance based on the statistics of the Euclidean distance at the output of a frequency-selective channel. From this theoretical framework, we propose a novel transmit-diversity scheme between subsequent HARQ transmissions, called phase-precoding, which allows the mitigation of intersymbol interference for slow time-varying channels. Then, with the help of our analytical tools, we revisit another transmit-diversity scheme which is the bit-interleaving diversity scheme. In particular, we emphasize the double advantage offered by this diversity scheme including the inherent modulation diversity in addition to the intersymbol interference reduction. Subsequently, we perform a comparative study between phase-precoding and bit-interleaving diversity schemes under iterative and non-iterative receiver structures. Finally, we introduce a new adaptive retransmission protocol for a multi-layer transmission scheme for the mitigation of inter-layers interference for rapidly time-varying channels using limited feedback information.