This thesis contributes to the literature in three main areas of research about capital structure: the determinants of capital structure, the profitability and the labour demand. (i) The theoretical basis of the determinants of capital structure shows that there are three models that explains the capital structure: Trade-Off theory, Pecking Order theory and Market Timing theory. Further, the empirical evaluation shows a positive effect of the adjustment costs and the tangibility. On the other hand, growth opportunity, non-debt tax shield and profitability are negatively correlated with debt. (ii) The impact of capital structure on profitability can be explained by three essential theories: signal theory, tax theory and the agency costs theory. The empirical analysis allowed to distinguish three different groups of sectors: for the first group, the capital structure has no impact on profitability. The second, it is the group where the debt affects negatively the profitability in a linear way. The last group is characterized by the presence of a negative effect in a linear and nonlinear way. (iii) Theoretically, a negative impact of the capital structure on labour demand is expected. The empirical application shows heterogeneity of behavior between sectors regarding the impact of debt on the demand for labor; therefore, there are three different groups of sectors (i.e. no effect, negative linear effect, and linear and non linear negative effect). Furthermore, the magnitude of the effect of debt on the labour demand and on the profitability depends not only of the sector, but also of the size of company.