Supply chain management involves a wide range of activities. Among most of them, uncertainty exists inherently and always brings some consequence not expected. However, uncertainty is not considered much in conventional supply chain management. In the case where availability of resources is not what we expect, complexity of supply chain management increases. Taking constraints of uncertainty and availability into account, we aim to discuss supply chain management from different aspects. This thesis is an attempt of systematic and complete research from this point and we would like to offer some references to researchers and managers in supply chain. We focus on three classic sources of uncertainty: demand, manufacturing and distribution. For each source of uncertainty, we analyze its cause and its impact to the performance of the supply chain. Uncertainty is specified into concrete classic problem and an approach is proposed to solve it. Furthermore, bi-level newsboy problem as a miniature of supply chain, is focused under double uncertain environment. Treating uncertain variables is actually a treatment on operational level. The methods used offer good demonstration in treating uncertain variables in decision problems
