Nowadays, avatars and re-writings of the myth of the Grail take their inspiration from Literature because the first literary mention of the scheme appears at the end of the twelfth century in Perceval ou le conte du Graal by Chrétien de Troyes. Thanks to its ambivalent (pagan and christian) origins, the Grail anchored in the collective imaginary as a myth of redemption or, at least, an ideal to reach. If the chivalric medieval quest requires a remarkable rigor and the body and soul purity to deserve the revelation of the Holy Vessel mysteries, in our days, mass culture heroes have an access to its secrets by simplified “quest-igations”. The devaluation of the subject occurs through transpositions in different genres, mediums and medias but also in the way society receives the Grail legend. From Holy Grail to Grail, from Literature to mass culture, from the Holy Bible to TV shows, this study tends to show the aspects of these transpositions and tries to prove that there are echos and exchanges between these mediums via the Grail. Following that point of view, the theme functions also as a overhang for what some call “minor” culture and literature that can, however, under the Grail influence, become scientific and bring new pieces of reflection concerning the myth, society and Literature.