Echo-guidance and MR temperature active control for interstitial US Ablation in liver

A MR compatible interstitial US applicator was developed for percutaneous treatmentof hepatocellular carcinoma (HCC) under imaging control. This work was based on two experimentations : 1) In the first experimentation, performed in vivo on pig liver,macro-lésions corresponding to the fusion of several elementary lesions on 360° were realized percutaneously under echo-guidance. The macrolésions obtainedshowed a size similar to those obtained with RF in clinical practice. Moreover, in this study, the elementary lesions proved to be quite indifferent to the heat sink effect oflarge hepatic blood-vessels; 2) In the second experimentation, performed in vitro andin vivo on pig liver, MR temperature active control was obtained for the creation oflesions similar in size and aspect in all directions. This MR temperature active control appeared extremely interesting since the power applied and the time of application were very different according to the direction of the ultrasonic beam.

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Source https://theses.hal.science/tel-00692361
Author Delabrousse, Éric
Maintainer CCSD
Last Updated May 20, 2026, 11:54 (UTC)
Created May 20, 2026, 11:54 (UTC)
Identifier NNT: 2009LYO10104
Language fr
Rights https://about.hal.science/hal-authorisation-v1/
contributor Applications des ultrasons à la thérapie ; Université Claude Bernard Lyon 1 (UCBL) ; Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)
creator Delabrousse, Éric
date 2009-07-10T00:00:00
harvest_object_id 281a8887-884c-45e4-afd9-daa984e3dda1
harvest_source_id 3374d638-d20b-4672-ba96-a23232d55657
harvest_source_title test moissonnage SELUNE
metadata_modified 2026-03-30T00:00:00
set_spec type:THESE