Molecular docking is a very complex task that can not be deal by only one user. Based on this observation, we propose to study the cognitive workload distribution on group of users in collaboration. For this purpose, we implement a distributed platform to interactively manipulate and deform structures of the molecules. With this platform, we want to study the assets of the closely coupled collaboration but also highlight the constraints and the drawbacks. Based on three experimentations, the study validate the concept of workload distribution in the closely coupled collaboration. However, it highlights limits with coordination conflicts through communication problem. Moreover, some difficulties have been encountered with the dynamic in a group of collaborators.Based on these results, we proposed a new working configuration coupled with new haptic communication metaphors to improve the communication and the coordination between the members of the group. These propositions have been evaluated in a fourth experimentation introducing biologists. The results show the importance of the haptic communication to improve the coordination in closely coupled collaboration.
