The purpose of this study relies on a new approach of the ionizing radiation dosimetry through fluorescence measurement. We showed the existence of a correlation between the dose received by a scintillator and the quantity of light emitted using the time correlated single photon counting (TCSPC) method. From a fundamental point of view, we described the different processes taking place when a medium is irradiated, leading to fluorescence emission. We used Voltz's theory, which explains the temporal evolution of this emission. This theory describes the light emission as an addition of two processes, a fast and a delayed component. During this study an experimental multimodal platform was developed allowing us to acquire innovative data about fluorescence emission intensity under different linear energy transfer. This platform allows us to study the delayed fluorescence mechanisms, at a nanosecond timescale and at different temperatures, under continuous irradiation. From a dosimetric point of view, we demonstrated that the TCSPC method provide a better spatial resolution in the dose measurement, within the hadrontherapy frame, than that of the conventional method. . A dosimeter prototype was also developed during this study based on scintillating optic fibers. Satisfactory results were obtained motivating us to use the prototype for medical X and gamma radiation dosimetry.
