Behavioural neurogenic effects of antidepressants in a new model of anxiety/depression in adult Mouse

Depression is characterized by heterogeneous symptoms in several brain regions. One of them, the hippocampus, is related to a phenomenon called neurogenesis, which seems to be linked to the etiology of depression and to the response of antidepressants. The main goal of this work was to study the relationships between all the 4 steps of hippocampal neurogenesis and antidepressants action in a model of depression in adult mouse.