This paper presents the main results of a research programme that looked at the impact of specific polycentric urban forms on commuting patterns and intra-urban segregation. Our results point out three different models. Lyon presents an extended monocentrism, with visible and diffuse inequalities. Marseille is characterized by a consuming duocentrism that is doubly unequal in social terms. In Lille, we highlight a thrifty but socially excluding polycentrism. Further research works will test the relevance of these models on other European cities with over a million inhabitants.