Indicators of Benzodiazepine Use in Nursing Home Residents in France: A Cross-Sectional Study

Objectives: Little information is available about associations between nursing home (NH) structural and organizational aspects and benzodiazepine prescriptions, particularly for long-acting drugs. This study addressed this knowledge gap. Design: Cross-sectional study. Setting: One hundred seventy-five NHs from France. Participants: A total of 6275 NH residents, aged 86 years (+/- 8.2), and mostly women (73.7%). Measurements: Outcome measures were: (1) benzodiazepine and (2) long-acting benzodiazepine use. NH staff sent to research team all drug prescriptions in the week participants were included in the study; staff also recorded information on residents' characteristics, and NHs structure and internal organization. Binary logistic regressions were performed separately on total and long-acting benzodiazepine. Results: A total of 3350 persons took benzodiazepine; 577 took long-acting benzodiazepine. Subject-related characteristics were the main correlates of benzodiazepine use. NH characteristics were also related to this outcome: number of beds >= 91 (Odds Ratio (OR) 0.820, 95% Confidence Interval (CI) 0.682-0.986), special care unit (OR 1.131, 95% CI 1.000-1.279), pharmacy for internal usage (OR 1.341, 95% CI 1.128-1.594), and date records of the first prescription of psychotropics (OR 1.394, 95% CI 1.209-1.607). Pharmacy for internal usage was also associated with long-acting benzodiazepine (OR 1.374, 95% CI 1.076-1.754). Conclusions: NH structure-and organization-related indicators impact benzodiazepine use among NH residents. This finding is of particular importance because these indicators are more easily modifiable than subject-related characteristics. Therefore, NH directors and medical staff should be aware about this to implement feasible modifications for reducing inappropriate and chronic benzodiazepine use

Data and Resources

Additional Info

Field Value
Source ISSN: 1525-8610
Author Barreto de Souto, Philippe, Mathieu, Céline, Piau, Christine, Lapeyre-Mestre, Maryse, Bouget, Catherine, Cayla, Françoise, Vellas, Bruno, Rolland, Yves
Maintainer CCSD
Last Updated May 10, 2026, 06:13 (UTC)
Created May 10, 2026, 06:13 (UTC)
Identifier halshs-00847487
Language en
contributor Anthropologie bio-culturelle, Droit, Ethique et Santé (ADES) ; Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-Établissement Français du Sang Alpes-Méditerranée (EFS Alpes-Méditerranée) ; Établissement Français du Sang [La Plaine Saint-Denis] (EFS)-Établissement Français du Sang [La Plaine Saint-Denis] (EFS)
creator Barreto de Souto, Philippe
date 2013-05-10T00:00:00
harvest_object_id 1e5d24f4-dace-46e9-8b9a-59d4bb8c518f
harvest_source_id 3374d638-d20b-4672-ba96-a23232d55657
harvest_source_title test moissonnage SELUNE
metadata_modified 2026-04-02T00:00:00
relation info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jamda.2012.09.002
set_spec type:ART