Real time bio mechanical characterization of DNA damage under therapeutic radiation beams

We report the first real-time biomechanical measurement of DNA bundle degradation in solution when exposed to a therapeutic radiation beam. The Silicon Nano Tweezers and their microfluidic endure the harsh environment of radiation beams and still retain molecular-level accuracy. This result paves the way for both fundamental and clinical studies of DNA degradation under radiation for improved tumor treatment.

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Source Proceedings of 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, microTAS 2013
Author Perret, G., Lacornerie, T., Kumemura, M., Lafitte, N., Guillou, H., Jalabert, L., Lartigau, E., Fujii, T., Cleri, F., Fujita, H., Collard, D.
Maintainer CCSD
Last Updated May 7, 2026, 03:42 (UTC)
Created May 7, 2026, 03:42 (UTC)
Identifier hal-00940877
Language en
contributor Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 (IEMN) ; Centrale Lille-Institut supérieur de l'électronique et du numérique (ISEN)-Université de Valenciennes et du Hainaut-Cambrésis (UVHC)-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)
coverage Freiburg, Germany
creator Perret, G.
date 2013-05-07T00:00:00
harvest_object_id 8c57b74d-2703-444e-8dde-a79c376f9fc3
harvest_source_id 3374d638-d20b-4672-ba96-a23232d55657
harvest_source_title test moissonnage SELUNE
metadata_modified 2026-02-02T00:00:00
set_spec type:COMM