Novel 5-Hydroxytryptamine Receptor (5-HT1B) Antagonists Library designed to achieve subtype-selectivity

OTAVA focused library of 5-HT1B antagonists (1,836 compounds in total) has been designed using receptor-based virtual screening of pre-filtered compound collection docked into orthosteric and extended pockets of the 5-HT1B ligand binding site.

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Additional Info

Field Value
Source https://hal.science/hal-00869985
Author Andrey, Dmytrenko
Maintainer CCSD
Last Updated May 9, 2026, 11:42 (UTC)
Created May 9, 2026, 11:42 (UTC)
Identifier hal-00869985
Language en
contributor Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG) ; Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
creator Andrey, Dmytrenko
date 2013-11-04T00:00:00
harvest_object_id 8141ebaf-15f7-4149-bc79-53c76b4804eb
harvest_source_id 3374d638-d20b-4672-ba96-a23232d55657
harvest_source_title test moissonnage SELUNE
metadata_modified 2024-04-11T00:00:00
set_spec type:REPORT