Alkali Aggregate Reaction (AAR) and Delayed Ettringite Formation (DEF) cause expansion of the affected concrete that generally leads to cracking and decrease of its mechanical properties. As a consequence, these pathologies raise severe problems in terms of serviceability, sustainable operation of the concrete works and structural integrity. To manage with considered suffering structures, it is necessary to provide predictive models able to reassess their mechanical state. In this paper, we describe the RGIB model developed with this objective and we compare its predictions to the results of experimental tests specifically performed to validate it. The objective is to emphasize which processes are well taken into account and which improvements could be implemented.