Cytochrome b shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy

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Source ISSN: 0006-2952
Author Kotrbová, Věra, Mrázová, Barbora, Moserová, Michaela, Martínek, Václav, Hodek, Petr, Hudeček, Jiří, Frei, Eva, Stiborová, Marie
Maintainer CCSD
Last Updated November 4, 2026, 06:49 (UTC)
Created November 4, 2026, 06:49 (UTC)
Identifier hal-00722844
Language en
Rights https://about.hal.science/hal-authorisation-v1/
contributor Faculty of Science ; Univerzita Karlova [Praha, Česká republika] = Charles University [Prague, Czech Republic] = Université Charles [Prague, Republique tchèque] (UK)
creator Kotrbová, Věra
date 2011-08-05T00:00:00
harvest_object_id 15d62c6f-38bd-49ef-9097-9c5e3722e2bb
harvest_source_id 3374d638-d20b-4672-ba96-a23232d55657
harvest_source_title test moissonnage SELUNE
metadata_modified 2026-03-12T00:00:00
relation info:eu-repo/semantics/altIdentifier/doi/10.1016/j.bcp.2011.06.003
set_spec type:ART