Perfluoroalkylation of aliphatic thiols in the presence of sodium hydroxymethanesulfinate

Direct perfluoroalkylation of aliphatic thiols was performed in the presence of sodium hydroxymethanesulfinate (Rongalite). Reaction of mercaptoalkanoic esters with trifluoromethyl bromide gave the corresponding trifluoromethylthio ethers. Condensation of alkane dithiols with perfluoroalkyl iodides led mainly to fluorinated dithioethers. These alkylation reactions are interpreted as occurring via in situ formation of dialkyldisulfides.

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Source ISSN: 0022-1139
Author Tordeux, Marc, Anselmi, Elsa, Blazejewski, Jean-Claude, Wakselman, Claude
Maintainer CCSD
Last Updated May 6, 2026, 07:28 (UTC)
Created May 6, 2026, 07:28 (UTC)
Identifier hal-00094982
Language en
contributor Synthèse, interactions et réactivité en chimie organique et bioorganique (SIRCOB) ; Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS)
creator Tordeux, Marc
date 2000-05-06T00:00:00
harvest_object_id 39e2522d-e517-4c74-a36b-6754e624f900
harvest_source_id 3374d638-d20b-4672-ba96-a23232d55657
harvest_source_title test moissonnage SELUNE
metadata_modified 2023-03-24T00:00:00
relation info:eu-repo/semantics/altIdentifier/doi/10.1016/S0022-1139(00)00286-4
set_spec type:ART