alpha-EWG-Substituted Enones: Suitable Substrates for Ring-Closing Metathesis

The A ring of hexacyclinic acid has been synthesised, using a ring-closing metathesis involving an alpha-EWG-substituted enone as the key step. We have then explored the scope of this reaction, which gives access to various 5- and 6-membered rings.

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Source ISSN: 0936-5214
Author Toueg, Julie, Prunet, Joëlle
Maintainer CCSD
Last Updated May 7, 2026, 22:46 (UTC)
Created May 7, 2026, 22:46 (UTC)
Identifier hal-00091438
Language en
contributor Laboratoire de synthèse organique (DCSO) ; École polytechnique (X) ; Institut Polytechnique de Paris (IP Paris)-Institut Polytechnique de Paris (IP Paris)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)
creator Toueg, Julie
date 2006-05-07T00:00:00
harvest_object_id 687df1eb-648d-42c2-b1b6-0bd5b4afc3ae
harvest_source_id 3374d638-d20b-4672-ba96-a23232d55657
harvest_source_title test moissonnage SELUNE
metadata_modified 2025-08-20T00:00:00
set_spec type:ART