A regional model (Northeastern Brazil) of induced mal-nutrition delays ontogeny of reflexes and locomotor activity in rats

The aim of this study was to investigate the effects of malnutrition, induced by a regional basic diet (RBD), on motor development. RBD is a 7.87%-protein diet based on aliments typical of Northeastern Brazil, elaborated after nutritional investigation by Teodosio et al. (1979). Female rats were treated with RBD during lactation. The reflex ontogenesis and the development of locomotor activity in their offspring were assessed. Malnourished (MN) rats showed a delay in reflex maturation and in locomotor activity evolution. The decreased locomotor activity may be related to the reduced movement experiences induced by the delay in the reflex maturation. Occurring during the critical period of brain development, this fact could jeopardize all the steps in future locomotion evolution. The present results confirm deleterious effects of RDB-induced malnutrition on the somatic development and maturation of the nervous system (NS).

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Field Value
Source ISSN: 1028-415X
Author Barros, K.M.F.T., Manhaes de Castro, R., Lopez-De-Souza, S., Matos, R.J.B., Deiro, T.C.B.J., Cabral-Filho, J.E., Canon, F.
Maintainer CCSD
Last Updated May 8, 2026, 09:10 (UTC)
Created May 8, 2026, 09:10 (UTC)
Identifier hal-00090069
Language en
contributor Biomécanique et Bioingénierie (BMBI) ; Université de Technologie de Compiègne (UTC)-Centre National de la Recherche Scientifique (CNRS)
creator Barros, K.M.F.T.
date 2006-05-08T00:00:00
harvest_object_id 5301d026-8812-4b2c-80fe-1ab8b9e83a64
harvest_source_id 3374d638-d20b-4672-ba96-a23232d55657
harvest_source_title test moissonnage SELUNE
metadata_modified 2026-04-28T00:00:00
relation info:eu-repo/semantics/altIdentifier/doi/10.1080/10284150600772148
set_spec type:ART