Substrate selectivity of human cytochrome P450 2C9: importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid

12 pages

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Source Archives of biochemistry and biophysics.
Author Melet, Armelle, Assrir, Nadine, Jean, Pascale, López-García, Maria Pilar, Marques-Soares, Cristina, Jaouen, Maryse, Dansette, Patrick, M., Sari, Marie-Agnès, Mansuy, Daniel
Maintainer CCSD
Last Updated May 19, 2026, 08:34 (UTC)
Created May 19, 2026, 08:34 (UTC)
Identifier hal-00069626
Language en
contributor Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques (LCBPT - UMR 8601) ; Université Paris Descartes - Paris 5 (UPD5)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)
creator Melet, Armelle
date 2003-05-19T00:00:00
harvest_object_id cff6314a-4041-49f0-8c7b-882d06b4dad9
harvest_source_id 3374d638-d20b-4672-ba96-a23232d55657
harvest_source_title test moissonnage SELUNE
metadata_modified 2026-05-08T00:00:00
relation info:eu-repo/semantics/altIdentifier/doi/10.1016/S0003-9861(02)00548-9
set_spec type:ART