16 datasets found

Growth hormone (GH) is a paradoxical hormone. Historically described as the major regulator of postnatal growth it is now recognised as a cytokine synthesized in many...

At the plasma membrane, both NGF receptors have been shown to localized to lipid rafts, specific subdomains that are enriched in cholesterol, sphingolipids and the...

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Tyk2 is a member of the Jak family of tyrosine kinases (Jak1, Jak2, Jak3 and Tyk2), which are indispensable components of -helical cytokine signaling cascades....

La voie de signalisation Notch est une voie de signalisation conservée et primordiale aussi bien pour le développement des métazoaires que la maintenance de leurs...

The conserved family of protein kinases SNF1/AMPK/SnRK1 (yeast/mammals/plants) is considered as a central element of cell metabolism regulation by controlling both...

Depuis 2002, l’église du prieuré rural clunisien de Saint-Jean de Todon fait l’objet d’une fouille programmée. Cet édifice cultuel est situé sur un plateau calcaire...

L’ouverture à la concurrence du réseau ferroviaire européen est une des volontés de la Commission Européenne. Celle-ci s’est concrétisée par des réformes tant...

Signalling pathways allow cells to perceive and exchange information under the form of chemical signals. Such a signal generates a response of the cell through the...

Huntington's disease (HD) is caused by a polyglutamine expansion in the huntingtin protein.<br />This mutation confers new properties on this protein, including...

Despite the complexity of the transformation process, several model systems have been developed in which normal cells are transformed in a step-wise manner by...

This thesis analyses the signaling load in intelligent large scale networks as well as the network selection strategies in the heterogeneous environment. The main...

Elastic fibres are composed of elastin and fibrillin-1 rich microfibrils, whose genetic mutations result in severe cardiovascular pathologies characterized by aortic...

Le présent article a pour but de décrire les travaux de recherche et développement d’une ontologie du système européen de contrôle-commande et signalisation...

ERTMS is the standard railway control-command and signaling system which aims to ensure railway interoperability throughout Europe while enhancing safety and...

Anti-Müllerian hormone (AMH) is a member of the TGF-ß superfamily. AMH is well known for its role in Müllerian duct regression in male fetuses. Postnatally, AMH is...