-
Role of Nectins in the recognition of tumor cells by gamma-delta T cells
T cells that express a γδ TCR (γδ T cells) are T cells that recognize non-conventional antigens independently of the MHC (major histocompatibility complex). In humans,... -
BCG immunotherapy for bladder cancer : characterization and modeling of the b...
Intravesical instillation of bacillus Calmette-Guérin (BCG) for non-muscle invasive bladder cancer is one of the few examples of successful immunotherapy in the... -
CD4+ T cells and regulatory T cell functions in immunotherapy and in the path...
Cerebral accumulation of aggregated Aβ40-42 peptides is among the major pathological hallmarks of Alzheimer's disease (AD). In spite of encouraging results of Aβ... -
Plasmacytoid dendritic cells and viral infections : physiopathologic role and...
The immune control of HBV infection is essential for viral clearance. The virus is able to modulate the immune system to escape this control. The mechanisms involved... -
Characterization of tumor associated alterations of myeloid and plasmacytoid ...
Dendritic cells (DC) as professional antigen presenting cells, are key regulators of adaptive immune responses. Among them, plasmacytoid dendritic cells (pDC) are... -
Optimisation of a targeted therapy by combining with a immunotherapy : phase ...
Imatinib mesylate (IM) was the first tyrosine kinase inhibitor to be successfully used in clinical practice and its introduction has revolutionized the management of... -
Immunotherapies of hepatocellular carcinoma and hepatitis C virus infection
The hepatitis C virus (HCV) is a major cause of hepatocellular carcinoma (HCC),whose treatments are of limited efficacy. The liver transplantation (LT) is the optimal... -
Use of a monoclonal antibody anti-Tn in cancer immunotherapy
Pas de résumé en anglais -
Study of mechanisms of action of an immunotherapy by triacyl lipid A in humans
Immunotherapy acting at the primary tumor site and preventing the development of metastases is one of the strategies for treatment of patients with cancer. To improve... -
Tumor associated regulatory CD4+ T cell in breast cancer, recruitment, and ro...
Tumor immunosbversion favors disease progression and is mediated by increased IL-10 secretion, reduced type-I IFN production and regulatory T cell (Treg) accumulation...
