6 datasets found

Autoimmune myasthenia gravis (MG) is a muscular disease mediated by autoantibodies, mainly directed against the acetylcholine receptor (AChR). The pathogenic...

Idiopathic inflammatory myopathies (IIM) are severe inflammatory muscle disorders with life threatning complications. Treatments are partially efficacious and have...

Dysregulated activation of T cells leads to pathogenic immune response to self-antigens. Despite an increasing use of high dose therapy of intravenous gammaglobulin...

Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease. It is mainly characterized by B cell and T cell infiltration in lacrimal and salivary glands (SG)...

Costimulation pathways are described as central in T cell activation and the control of autoimmune responses. We previously reported that NOD mice that are deficient...

The chronic infection by the hepatitis C virus (HCV) can be associated among some patients with extrahepatic auto-immune demonstrations. The question arises concerning...