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Study of cell death and resistance mechanisms in cancer cells for the develop...
Apoptosis is a programmed cell death process necessary for tissue homeostasis duringdevelopment. Cancer cells acquire the capacity to evade apoptosis. Restoring tumor... -
Atrophy and muscle recovery in the immobilized rat : the role of nutrition
Sarcopenia, the age-related muscle mass loss, might be partially explained by an impairedmuscle mass recovery of skeletal muscle mass after a catabolic state. Thus,... -
Effect of transiant and permanent permeability transition pore opening on NAD...
Several studies have shown that ischemia/reperfusion injury is strongly related to mitochondrial dysfunction. These studies have mostly focused on the involvement of... -
Synthesis of aromatic compounds, potential anticancer agents involved in apop...
Apoptosis or programmed cell death is a genetically and complex process required for normal development. It is involved in maintenance of tissue homeostasis and... -
Molecular targets of myostatin involved in muscle hypertrophy in mouse and ca...
Diplôme : Dr. d'Université -
Functional characterization of the peroxydase glutathone 5
The epididymal maturation is a key element in the development of the ability of the male gamete to fertilize the oocyte. Among the many components involved in this... -
Apoptosis of spermatozoa and male fertility
In order to have a better insight into the implications of apoptosis markers in human ejaculated spermatozoa, the aim of our study was to measure these markers in the... -
Lignes de fuite et négativité : de l'apoptose dans une perspective deleuzienne.
This dataset has no description
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Identification of a new mechanism that controls the homeostasis of iNKT and M...
Invariant natural killer T (iNKT) lymphocytes represent a peculiar T cell-lineage that differs from conventional T cells by its development, function, and ligands it... -
Innate Immune Response of plasmacytoid dendritic cells during retroviral stim...
Innate immune response which is characterized by antiviral cytokines such as interferon-alpha (IFN-, is essential during viral infections. Plasmacytoid dendritic... -
Study of mechanisms involved in the resistance to apoptosis of cells infected...
- Résumé en anglais : Our team is working on the mechanisms of apoptosis induced by nutlin-3, a small molecule which binds to MDM2 and activates p53, in different... -
Control of EGFR-L858R oncogenic signaling pathway by the p14ARF tumor suppres...
Control of EGFR-L858R oncogenic signaling pathway by the p14ARF tumor suppressor in lung adenocarcinoma. The EGF receptor (EGFR) is a strong oncogene involved in lung... -
Cellular and molecular targets of silibinin, a natural flavonoid, in colorect...
Colorectal cancer (CRC) is the second most common cause for cancer-related deaths in Europe and in the USA. Because of the limited efficacy and considerable toxicity... -
Physiopathology of chikungunya in acute and chronic stages of the disease in ...
Chikungunya is an Alphavirus transmitted by mosquitoes (Aedes) and which causes fever, rash, myalgia and arthralgia. The disease (CHIKVD) is transient but severe forms... -
DESIGN, SYNTHESIS AND PHARMACOLOGICAL VALUATION OF γ-CARBOLINES,<br />POTENTI...
Two key enzymatic systems in the inflammation process revealed being implicated <br />in many cancers (colon, pancreas, breast, lung) and more particularly in... -
Acidic extracellular pH shifts colorectal cancer cell death from apoptosis to...
International audience -
UNC5H dependence receptor apoptotic signalisation and tumorigenesis
Dependence receptors are a new class of pro-apoptotic receptor able to induce a survival signal in presence of their ligand and, on the opposite site to induce... -
Telomerase and neuroblastoma tumor fate
Telomerase is a ribonucleoprotein consisting of an RNA component (hTR) that serves as atemplate for the addition of telomeric sequences at the ends of chromosomes and... -
Role of p53 pathway in the response of soft tissue sarcomas to TNF-alpha trea...
Introduction: Although named for its antitumor properties, TNF-a is implicatedin a wide spectrum of diseases including chronic inflammation, autoimmunity andcancer. It... -
First pharmacomodulations of meiogynin A, an inhibitor of the Bcl-xL/Bak inte...
The control of the apoptosis is one of the new modern key to fight against the cancer. The apoptosis is the self destruction of cells, part of the homeostasis, which...
