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ADF/cofiline, an essential factor that controls actin dynamics during cell mo...
During my thesis, I have studied the pivotal role of ADF/cofilin, a protein that binds to the actin cytoskeleton, specifically decorates ‘old' actin filament parts,... -
SHANK3 mutations identified in autism lead to modification of dendritic spine...
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ARHGAP10 is necessary for alpha-catenin recruitment at adherens junctions and...
E-cadherin mediates the formation of adherens junctions between epithelial cells. It serves as a receptor for Listeria monocytogenes, a bacterial pathogen that enters... -
Clathrin is required for Scar/Wave mediated lamellipodium formation
The Scar/Wave complex (SWC) generates lamellipodia through Arp2/3-dependent polymerization of branched actin networks. In order to identify new SWC regulators, we... -
Slow dynamics and internal stress relaxation in bundled cytoskeletal networks
Crosslinked and bundled actin filaments form networks that are essential for the mechanical properties of living cells. Reconstituted actin networks have been... -
Mechanical model of cytoskeleton structuration during cell adhesion and sprea...
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Magnetic beads as force sensors : application to actin filaments growth pressure
Superparamagnetic colloids are used in many studies to apply a force or a torque on biological systems such as cells or DNA molecules. The physical process by which... -
Actin network architecture can determine myosin motor activity.
The use of micropatterned substrates to control actin network self-assembly is protected by patent EP2011/063676 -
Epithelial protein lost in neoplasm (EPLIN) interacts with α-catenin and acti...
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CKIP-1 scaffold protein involvement in actin cytoskeleton and membrane remode...
Skeletal muscle cells are composed of contractile elements wrapped in a membrane network. Formation and maintenance of skeletal muscle involve muscle precursor... -
Diameter-dependent bending dynamics of single-walled carbon nanotubes in liquids
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Spatial organization of the extracellular matrix regulates cell-cell junction...
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Continuous droplet interface crossing encapsulation (cDICE) for high throughp...
We report on a continuous droplet interface crossing encapsulation (cDICE) technique for the high-yield production of microscopic vesicles tunable in size and content.... -
Molecular mechanisms involved in Duchenne Muscular Dystrophy: Analysis of int...
The characterization of the interactions of different biomolecules such as proteins and peptides with lipids, constitute a crucial step for better understanding the... -
Dynamique des réseaux d'actine d'architecture contrôlée.
During my thesis I have developed different projects in order to tackle the problem of actin network dynamics and organization as well as the molecular mechanism at... -
TRAIL signalling regulation by ezrin
Background and Aim: TRAIL has sparked a growing interest in oncology due to its ability to selectively trigger cancer cell death while sparing normal cells. The... -
New functions of p21Cip1 in cytoskeletal dynamics of human mammary epithelial...
CDKN1A gene was initially identified as a target of the tumor suppressor p53. The ability to inhibitcyclin-dependant kinase and PCNA activities confers to its product,... -
Leishmania donovani lipophosphoglycan inhibits phagosomal maturation via acti...
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Polarized Cdc42 activation promotes polar body protrusion and asymmetric divi...
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Pivotal role of actin binding proteins for proper microvilli function and pla...
Covering the apex of intestinal cells, microvilli are microscopic membrane protrusions structured by a network of actin filaments organized by actin binding proteins....
