19 datasets found

International audience

Skeletal muscle cells are composed of contractile elements wrapped in a membrane network. Formation and maintenance of skeletal muscle involve muscle precursor...

International audience

International audience

We report on a continuous droplet interface crossing encapsulation (cDICE) technique for the high-yield production of microscopic vesicles tunable in size and content....

The characterization of the interactions of different biomolecules such as proteins and peptides with lipids, constitute a crucial step for better understanding the...

During my thesis I have developed different projects in order to tackle the problem of actin network dynamics and organization as well as the molecular mechanism at...

Background and Aim: TRAIL has sparked a growing interest in oncology due to its ability to selectively trigger cancer cell death while sparing normal cells. The...

CDKN1A gene was initially identified as a target of the tumor suppressor p53. The ability to inhibitcyclin-dependant kinase and PCNA activities confers to its product,...

International audience

International audience

Covering the apex of intestinal cells, microvilli are microscopic membrane protrusions structured by a network of actin filaments organized by actin binding proteins....

International audience

International audience

Actin filaments play a fundamental role in cell mechanics: assembled into networks by a large number of partners, they ensure cell integrity, deformability, and...

We studied the growth of asymmetric cellular contacts : adherens junctions and focal contacts. We showed, by imaging, micromanipulation and cellular assembly...

Bone remodeling is a physiological process by which old bone is replaced by new bone. Osteoclasts are multinucleated giant cells of the monocytic lineage. Their...

absent

International audience