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Study of mechanisms involved in the resistance to apoptosis of cells infected...
- Résumé en anglais : Our team is working on the mechanisms of apoptosis induced by nutlin-3, a small molecule which binds to MDM2 and activates p53, in different... -
Analyse of NADPH Oxidases and oxidative stress in dendritic cells.
Dendritic cells play an important role in the development of immune responses; the numerous functional activities of DC, among them their important phagocytic... -
Recommender systems in industrial contexts
This thesis deals with automatic recommendation systems. Automatic recommendation systems are systems that allow, through data mining techniques, to recommend... -
Spin dynamics of the unconventional superconductor CeCoIn5
In this thesis, the spin dynamics of CeCoIn5 has been studied by inelastic neutron scattering. CeCoIn5 presents the highest critical temperature ( Tc = 2.3 K) among... -
Modeling the impact of cognitive biases on industrial dynamics : Orphaninnova...
The purpose of the thesis is the study of industrial dynamics, in particular cognitive biases that lead to the lock-in of these dynamics. If innovation processes... -
Large cavity cyclodextrin-based macrocyclic ligands : synthesis, coordination...
Cyclodextrins (CDs) are cyclic oligosaccharides of various sizes containing several α-(1→4)-linked D-(+)- glucopyranose units. The commercially available ones comprise... -
Study of Frequency reconfigurable miniature antennas with active components
Current telecommunication systems and especially mobile terminals require compact antennas with significant bandwidth. But one of the well-known drawbacks of... -
Regulation of cell adhesion by CRF2 : A stress effector in the digestive tract
Stress is involved in the initiation and the exacerbation of several diseases especially in the intestine. Stress effects depends on the expression of specific... -
Role of PTP in beta cell apoptosis
PTP involvement in β pancreatic cell death Hyperglycemia, hyperfructosemia and ischemia-reperfusion play a major role in the progression of β cell loss in diabetes... -
Injectable Artemisinin loaded nano-assembled systems made with biotransesteri...
Artemisinin (ART), an endoperoxide sesquiterpene lactone antimalarial drug isolated from a Chinese medicinal herb (Artemisia annua), has a fast action against... -
Déformation et anisotropie sismique sous les frontières de plaques décrochant...
This work provides new constraints on the development and on the distribution of the deformation in the upper mantle and particularly beneath transform plate... -
Synthesis of new ligands of CD1d receptor : applications to anti-tumor vaccin...
The aim of this project was to optimize the anti-tumor immune response induced by dendritic and iNKTs cells, in response to KRN7000 (a-galactosyl-ceramide), which... -
Geophysical and geochemical characterization of water-rock interactions at th...
In coastal carbonate aquifers submitted to a saline intrusion, water - rock interactions processes at the interface between freshwater and saltwater are a cause for... -
Fiabilité des dispositifs HEMT en technologie GaN
Reliability in GaN based devices still motivates numerous studies because the involved degradation mechanisms are different from that in III-V narrow bandgap devices.... -
Monte Carlo methods for sampling high-dimensional binary vectors
This thesis is concerned with Monte Carlo methods for sampling high-dimensional binary vectors from complex distributions of interest. If the state space is too large... -
Deuterium/hydrogen exchanges in interstellar ices
The interstellar medium where stars are formed consists of a dilute gas which is dominated by molecular hydrogen and dust grains less than a few microm in size. The... -
Breaking the limits of facial identification in video-surveillance context.
The person identification systems based on face recognition are becoming increasingly widespread and are being used in very diverse applications, particularly in the... -
Development of anti-tumor immunotherapy mediated by type III secretion system...
Due to the endowed effective ability to deliver antigen to cytoplasm of APCs in vivo, T3SS based attenuated bacterial vectors attracted more and more attention for... -
Improvements on Dislocation Dynamics Codes for the study of irradiated RPV fe...
The present work is part of a larger multi-scale effort aiming to increase knowledge of thephysical phenomena underneath reactor pressure vessel irradiation... -
How to justify the multiple banking of SMB?
Our thesis focuses on SMB bank financing in France. This Kind of firms tends to borrow from more than one bank to finance their investments in recent years. The choice...
