@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00982618v1> a dcat:Dataset ;
    dct:description """
              Prognosis and management of patients with chronic hepatitis C depends on the degree of liver fibrosis which is classically assessed by histological examination of a liver biopsy. However, liver biopsy is an invasive procedure and histological examination is impaired by sampling bias and fair reproductibility. Recently, new tests allow for a non-invasive evaluation of liver fibrosis : fibrosis blood tests and transient elastography (Fibroscan). Since December 2008, the French Health Authority has recommanded these tests as first-line exams for the assessment of fibrosis/cirrhosis in patients with chronic hepatitis C. However, these recommendations do not specify the practical use of these tests. In addition, the accuracy of non-invasive fibrosis tests has mainly been globally evaluated and the implement a methodology to improve the accuracy of the non-invasive diagnosis of liver fibrosis in hepatitis C. We developed several methodological concepts : fibrosis tests adapted to the diagnostic target, synchronous combinations of tests, association of intervals of reliable diagnosis. These new concepts were finally used to develop a new non-invasive classification of liver fibrosis, easy to use and very significantly more accurate than those actually used in clinical practice.
            """ ;
    dct:identifier "tel-00982618" ;
    dct:issued "2026-05-05T13:27:01.474246"^^xsd:dateTime ;
    dct:language "fr" ;
    dct:modified "2026-05-05T13:27:01.474250"^^xsd:dateTime ;
    dct:publisher <https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> ;
    dct:title "Methodology to improve the accuracy of the non-invasive diagnosis of liver fibrosis in chronic hepatitis C" ;
    dcat:contactPoint [ a vcard:Organization ;
            vcard:fn "CCSD" ] ;
    dcat:distribution <https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00982618v1/resource/b26db72f-c099-40af-94f4-5014ceca5253> ;
    dcat:keyword "biopsie",
        "fibroscan",
        "fibrose",
        "hepatite-chronique-c",
        "infoeu-reposemanticsdoctoralthesis",
        "methodologie",
        "sdvbbmlife-sciences-q-biobiochemistry-molecular-biology",
        "test-sanguins-de-fibrose",
        "tests-non-invasifs",
        "theses" ;
    dcat:landingPage <https://theses.hal.science/tel-00982618> .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00982618v1/resource/b26db72f-c099-40af-94f4-5014ceca5253> a dcat:Distribution ;
    dct:format "HTML" ;
    dct:issued "2026-05-05T13:27:01.482114"^^xsd:dateTime ;
    dct:modified "2026-05-05T13:27:01.463098"^^xsd:dateTime ;
    dct:title "Methodology to improve the accuracy of the non-invasive diagnosis of liver fibrosis in chronic hepatitis C" ;
    dcat:accessURL <https://theses.hal.science/tel-00982618> .

<https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> a foaf:Agent ;
    foaf:name "test_moissonnage_selune" .

<https://theses.hal.science/tel-00982618> a foaf:Document .