@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00952865v1> a dcat:Dataset ;
    dct:description """
              Vitamin D status can be determined by a radioimmunoassay measurement of 25-hydroxyvitamins D2 and D3 in plasma. For this purpose, 5 vitamin D haptens with different terminal carboxylic acid side chains were synthesised from vitamin D2. Rabbits, rats and mouse antibodies were generated by immunisation with bovine serum albumin conjugates of these 5 haptens. Histamine conjugates gave precursors of the radioiodinated tracers. 25-hydroxyvitamin D2 and D3 antibodies were obtained from all these animals with more or less equal recognition. Spleen cells from 3 rats immunised were fused with mouse myeloma cells. Two different hybridoma clones secreting monoclonal antibodies with equal response for the two vitamins and no cross-reaction with 1α,25-dihydroxyvitamin D were selected.
            """ ;
    dct:identifier "tel-00952865" ;
    dct:issued "2026-05-06T05:22:03.199585"^^xsd:dateTime ;
    dct:language "fr" ;
    dct:modified "2026-05-06T05:22:03.199590"^^xsd:dateTime ;
    dct:publisher <https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> ;
    dct:title "Synthesis of vitamin D haptens and production of monoclonal anti-25-hydroxyvitamin D antibodies for the optimization of a simultaneous 25-hydroxyvitamins D2 and D3 immunoassay" ;
    dcat:contactPoint [ a vcard:Organization ;
            vcard:fn "CCSD" ] ;
    dcat:distribution <https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00952865v1/resource/04834840-5b9d-420f-b1b5-b50c185f153b> ;
    dcat:keyword "anticorps-anti-25-hydroxyvitamine-d",
        "chimorgachemical-sciencesorganic-chemistry",
        "haptenes-25-hydroxyvitamines-d2-et-d3",
        "immunodosage",
        "infoeu-reposemanticsdoctoralthesis",
        "theses",
        "traceurs",
        "vitamine-d" ;
    dcat:landingPage <https://theses.hal.science/tel-00952865> .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00952865v1/resource/04834840-5b9d-420f-b1b5-b50c185f153b> a dcat:Distribution ;
    dct:format "HTML" ;
    dct:issued "2026-05-06T05:22:03.202461"^^xsd:dateTime ;
    dct:modified "2026-05-06T05:22:03.181847"^^xsd:dateTime ;
    dct:title "Synthesis of vitamin D haptens and production of monoclonal anti-25-hydroxyvitamin D antibodies for the optimization of a simultaneous 25-hydroxyvitamins D2 and D3 immunoassay" ;
    dcat:accessURL <https://theses.hal.science/tel-00952865> .

<https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> a foaf:Agent ;
    foaf:name "test_moissonnage_selune" .

<https://theses.hal.science/tel-00952865> a foaf:Document .

