Automatic delineation optimization of lung tumors on PET / CT images for dosimetry planning in radiotherapy treatment
type: Dataset
description: Tumor delineation is a critical aspect in radiotherapy planning treatment and is usually performed on the anatomical images of a computed tomography (CT) scan. Recently, for non-small cell lung cancer, it has been recommended to use functional Positron Emission Tomography (PET) images to take into account the target biological characteristics. However, today, there is no satisfactory segmentation technique for PET images in clinical applications. In the present study, a solution of this problem is proposed. Methods: The optimizations of tumor delineation consisted primarily on the thresholds adjustment directly from patients, rather than phantoms. The development and the validation of this adjustment were done by comparing segmented lesions on PET images with two different gold standards: measurements performed on CT images of the selected lesions and histological measurements of surgically removed tumors. Results: For lesions greater than 20 mm, our segmentation technique showed very good estimation of histological measurements (mean difference diameter between measured and calculated data equal to +1.5 ± 8.4 %) and an acceptable estimation of CT measurements. For lesions smaller or equal to 20 mm, the method showed a large gap with the measurements derived from histological or CT data. Conclusion: This novel segmentation technique shows very high accuracy for the lesions of large axes between 2 and 4.5 cm. Nevertheless, it does not correctly evaluate smaller lesions probably because of the partial volume effect
landing page: https://theses.hal.science/tel-00864905
identifier: NNT: 2011LYO10138
keyword: dosimetry-planning
keyword: infoeu-reposemanticsdoctoralthesis
keyword: lesion
keyword: lung-tumor
keyword: planification-dosimetrique
keyword: positron-emission-tomography-pet
keyword: sdvmheplife-sciences-q-biohuman-health-and-pathology
keyword: segmentation-technique
keyword: technique-de-segmentation
keyword: theses
keyword: tomographie-par-emission-de-positon-tep
keyword: tumeur-pulmonaire
issued: 2026-05-09T15:24:23.078837
modified: 2026-05-09T15:24:23.078842
language: fr
contact point: Organization
  fn: CCSD

test_moissonnage_selune
type: Agent

Automatic delineation optimization of lung tumors on PET / CT images for dosimetry planning in radiotherapy treatment
type: Distribution
format: HTML
access URL: https://theses.hal.science/tel-00864905
issued: 2026-05-09T15:24:23.086130
modified: 2026-05-09T15:24:23.066647