oai-hal-tel-00833191v1
type: Dataset
description: Efficient and ecofriendly synthetic methodologies have always constituted an important area of research in modern organic chemistry. Lewis superacid catalysis has contributed in the improvement of many synthetic processes. We have developed some cycloisomerization reactions including Friedel-Crafts type reaction, giving access to a set of interesting polycyclic structures with good yields and selectivities. The use of a catalytic amount of Bi(OTf)3 (1 to 10 mol%), has allowed the activation of olefins, non-activated allenes and of 1,3-dienic systems. This atom economy methodology can prevent the formation of by-products and the catalyst can be recycled without loss of activity. Intra- and intermolecular approaches, tandem and cascades reactions, as well as mechanistic studies were conducted to enable a better understanding of the reactivity and its limitations to reach a wider range of structures. The developed methodologies were applied to the field of flavors and fragrances in the synthesis of Calone 1951® analogues, and for the preparation of chromans, indanes and tetralins type functionalized structures, for a better understanding of the structure/odor relationship.
identifier: NNT: 2013NICE4009
issued: 2026-05-10T18:20:13.805102
language: fr
modified: 2026-05-10T18:20:13.805108
title: Formation de composés polycycliques par activation de doubles liaisons : approche catalytique intra et intermoléculaire de réactions de type Friedel-Crafts : applications au domaine des arômes et parfums
contact point: Organization
  fn: CCSD
keyword: 13-diene
keyword: allene
keyword: benzosuberane
keyword: bismuth-triflate
keyword: calone-1951
keyword: catalyse
keyword: catalysis
keyword: chimothechemical-sciencesother
keyword: chromane
keyword: cyclisation
keyword: cyclization
keyword: diene-13
keyword: friedel-crafts
keyword: indane
keyword: infoeu-reposemanticsdoctoralthesis
keyword: olefine-non-activee
keyword: tetraline
keyword: theses
keyword: triflate-de-bismuth
keyword: unactivated-olefine
landing page: https://theses.hal.science/tel-00833191

https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00833191v1/resource/be75cfa5-7c09-4254-8aac-85aa951b38f3
type: Distribution
format: HTML
issued: 2026-05-10T18:20:13.813912
modified: 2026-05-10T18:20:13.787048
title: Formation de composés polycycliques par activation de doubles liaisons : approche catalytique intra et intermoléculaire de réactions de type Friedel-Crafts : applications au domaine des arômes et parfums
access URL: https://theses.hal.science/tel-00833191

test_moissonnage_selune
type: Agent