Objective measure of physical activity in free living and relations with adiponectin
type: Dataset
description: Accurate measurements of physical activity in free living are needed to establish what dose of physical activity is necessary for obtaining a specific health benefits. The first aim of this work was to validate the Actiheart (which combines heart rate and accelerometry sensors) with doubly labeled water (DLW). We show a good level of concordance between physical activity energy expenditure (PAEE) estimated by Actiheart and DLW. Individualization of the relationship between heart rate and PAEE by an incremental test is needed for an accurate estimate of the PAEE at the individual level and to evaluate changes induced by an intervention. In laboratory, we show that the accuracy of Actiheart is activitydependent. This requires the establishment of their recognition from new sensors and mathematical models. Adiponectin, hormone secreted by adipose tissue, has a role in energy metabolism and its secretion decreases with obesity. However the effects of physical activity remain in contradiction in published studies. The second objective of this work was to evaluate the effect of physical activity and intervention with weight control on plasma adiponectin. We show that the total and high molecular weight adiponectin were negatively associated with modifications of the physical activity level. Further work is however necessary to understand the mechanisms underlying this modulation of plasma adiponectin which does not seem related to changes in synthesis in adipose tissue or muscle.
identifier: NNT: 2011LYO10301
issued: 2026-05-11T05:42:19.719478
language: fr
modified: 2026-05-11T05:42:19.719482
contact point: Organization
  fn: CCSD
keyword: actiheart
keyword: activite-physique
keyword: adiponectin
keyword: adiponectine
keyword: adiponectine-de-haut-poids-moleculaire
keyword: calorimetrie-indirecte
keyword: doubly-labeled-water
keyword: eau-doublement-marquee
keyword: high-molecular-weight-adiponectin
keyword: inactivite-physique
keyword: indirect-calorimetry
keyword: infoeu-reposemanticsdoctoralthesis
keyword: measurement-of-physical-activity
keyword: mesure-de-lactivite-physique
keyword: physical-activity
keyword: physical-inactivity
keyword: sdvmheplife-sciences-q-biohuman-health-and-pathology
keyword: theses
landing page: https://theses.hal.science/tel-00820170

Objective measure of physical activity in free living and relations with adiponectin
type: Distribution
format: HTML
issued: 2026-05-11T05:42:19.752677
modified: 2026-05-11T05:42:19.701428
access URL: https://theses.hal.science/tel-00820170

test_moissonnage_selune
type: Agent