Role of VE-statin (EGFL7) in tumorigenesis
type: Dataset
description: Angiogenesis, which corresponds to the growth of new blood vessels from pre-existing vessels; is necessary for tumor growth and is an attractive target for anticancer therapy. Since 2004, several antiangiogenic therapies against colon, lung, breast, kidney cancers have been developed and used in clinic.VE-statin/egfl7 was discovered by our team in 2003. It is specifically expressed by endothelial cells during embryonic development and vascular remodelling. Several publications have described the role of VE-statin in vessel formation. VE-statin expression by human tumors has been recently associated with a higher grade and metastatic score and with a poorer prognosis in hepatocellular carcinoma, glioma and colorectal cancer.The aim of my work was to develop tools for the study of the functions of VE-statin in tumor growth and angiogenesis. This analysis allows a better understanding of the mechanisms which modulate tumor progression.
landing page: https://theses.hal.science/tel-00693157
identifier: NNT: 2011LIL2S017
keyword: adherence-leucocytaire
keyword: cancer
keyword: infoeu-reposemanticsdoctoralthesis
keyword: sdvmheplife-sciences-q-biohuman-health-and-pathology
keyword: theses
keyword: ve-statin
keyword: ve-statine
issued: 2026-05-20T05:51:08.651886
modified: 2026-05-20T05:51:08.651894
language: fr
contact point: Organization
  fn: CCSD

test_moissonnage_selune
type: Agent

Role of VE-statin (EGFL7) in tumorigenesis
type: Distribution
format: HTML
access URL: https://theses.hal.science/tel-00693157
issued: 2026-05-20T05:51:08.694839
modified: 2026-05-20T05:51:08.632985