Generation of stem cell-derived hepatic progenitors : application to familial hypercholesterolaemia
type: Dataset
description: Hepatocyte transplantation represents an alternative to liver for the treatment of metabolic diseases including familial hypercholesterolaemia. Embryonic stem cells (ES) and induced pluripotent stem cells (iPS) represent new sources of hepatic cells. We have developed an approach to differentiate human stem cells into hepatic cells and thus we have generated hepatic cells derived from iPS of familial hypercholesterolaemia patients.
landing page: https://theses.hal.science/tel-00684386
identifier: NNT: 2011PA114821
keyword: cellules-souches-pluripotentes-induites
keyword: criblage-therapeutique
keyword: developement
keyword: differentiation
keyword: embryonic-stem-cells
keyword: ex-vivo-gene-therapy
keyword: familial-hypercholesterolaemia
keyword: hepatocytes
keyword: humain
keyword: human-primate
keyword: hypercholesterolemie-familiale
keyword: induced-pluripotent-stem-cells
keyword: infoeu-reposemanticsdoctoralthesis
keyword: liver
keyword: low-density-lipoproteins-receptor
keyword: primate-non-humain
keyword: recepteur-aux-low-density-lipoproteins
keyword: sdvsalife-sciences-q-bioagricultural-sciences
keyword: therapeutic-screening
keyword: therapie-genique-ex-vivo
keyword: theses
issued: 2026-05-22T23:44:07.378854
modified: 2026-05-22T23:44:07.378860
language: fr
contact point: Organization
  fn: CCSD

test_moissonnage_selune
type: Agent

Generation of stem cell-derived hepatic progenitors : application to familial hypercholesterolaemia
type: Distribution
format: HTML
access URL: https://theses.hal.science/tel-00684386
issued: 2026-05-22T23:44:07.578745
modified: 2026-05-22T23:44:07.304814