Generation of stem cell-derived hepatic progenitors : application to familial hypercholesterolaemia
type: Distribution
access URL: https://theses.hal.science/tel-00684386
format: HTML
issued: 2026-05-22T23:44:07.578745
modified: 2026-05-22T23:44:07.304814

Generation of stem cell-derived hepatic progenitors : application to familial hypercholesterolaemia
type: Dataset
contact point: Organization
  fn: CCSD
keyword: criblage-therapeutique
keyword: developement
keyword: primate-non-humain
keyword: liver
keyword: differentiation
keyword: sdvsalife-sciences-q-bioagricultural-sciences
keyword: hepatocytes
keyword: hypercholesterolemie-familiale
keyword: ex-vivo-gene-therapy
keyword: therapeutic-screening
keyword: recepteur-aux-low-density-lipoproteins
keyword: induced-pluripotent-stem-cells
keyword: low-density-lipoproteins-receptor
keyword: familial-hypercholesterolaemia
keyword: theses
keyword: human-primate
keyword: therapie-genique-ex-vivo
keyword: humain
keyword: cellules-souches-pluripotentes-induites
keyword: embryonic-stem-cells
keyword: infoeu-reposemanticsdoctoralthesis
landing page: https://theses.hal.science/tel-00684386
description: Hepatocyte transplantation represents an alternative to liver for the treatment of metabolic diseases including familial hypercholesterolaemia. Embryonic stem cells (ES) and induced pluripotent stem cells (iPS) represent new sources of hepatic cells. We have developed an approach to differentiate human stem cells into hepatic cells and thus we have generated hepatic cells derived from iPS of familial hypercholesterolaemia patients.
identifier: NNT: 2011PA114821
issued: 2026-05-22T23:44:07.378854
language: fr
modified: 2026-05-22T23:44:07.378860

test_moissonnage_selune
type: Agent