@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00675243v1> a dcat:Dataset ;
    dct:description """
              For the individual patient with primary IgA nephropathy (IgAN), it remains a challenge to predict accurately the long term outcome at 10 and 20 years after disease onset. We studied it in a prospective cohort of 332 (237 males, 71.4%) biopsy-proven IgAN patients, the IGAN-STET-CO, aged at diagnosis of mean = 41.4 (SD=15.1) years, with a total exposure time of mean = 12.9 (9.5) y. Using three consensual risk factors (RF) simplified as dichotomous covariates : occurrence of hypertension, proteinuria ≥1 g/d, and severe pathological lesions (global optical score ≥8), we calculated an absolute renal risk (ARR) of dialysis/death (D/D), in analogy to the absolute cardiovascular risk. The ultimate prediction according to the number of RF present at diagnosis (ARR score: 0, 1, 2, or 3) was done by the Cox regression and the Kaplan-Meier survival methods. Overall, this ARR scoring permitted significant (P<0.0001) stratification of the risk. The cumulative incidence rate of D/D events (N=45), respectively at 10 and 20y, was 2 and 4% for ARR=0 (45.5% of all cases), 2 and 9% for ARR=1 (20.8%), 7 and 18% for ARR=2 (19.6%), and 29 and 64% for ARR=3 (N=47; 14.1%) in adequately treated patients. Effective control of hypertension and reduction of proteinuria improved survival without D/D when achieved. This absolute renal risk score evaluated at diagnosis, allowed accurate prediction of ultimate dialysis/death risk and was also validated in another cohort. This is a significant progress in the management of the individual patient with lgA nephropathy
            """ ;
    dct:identifier "NNT: 2010STET010T" ;
    dct:issued "2026-05-26T08:02:10.818033"^^xsd:dateTime ;
    dct:language "fr" ;
    dct:modified "2026-05-26T08:02:10.818040"^^xsd:dateTime ;
    dct:publisher <https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> ;
    dct:title "Predicting the risk for dialysis or death in IgA nephropathy" ;
    dcat:contactPoint [ a vcard:Organization ;
            vcard:fn "CCSD" ] ;
    dcat:distribution <https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00675243v1/resource/10a810a2-3b5f-4acf-89dc-ea9f1d66036c> ;
    dcat:keyword "dialyse",
        "iga",
        "iga-nephropathie",
        "infoeu-reposemanticsdoctoralthesis",
        "maladie-auto-immune",
        "maladie-renale-chronique",
        "proteinurie",
        "risque-renal-absolu",
        "sdvmheplife-sciences-q-biohuman-health-and-pathology",
        "theses" ;
    dcat:landingPage <https://theses.hal.science/tel-00675243> .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00675243v1/resource/10a810a2-3b5f-4acf-89dc-ea9f1d66036c> a dcat:Distribution ;
    dct:format "HTML" ;
    dct:issued "2026-05-26T08:02:10.839301"^^xsd:dateTime ;
    dct:modified "2026-05-26T08:02:10.770022"^^xsd:dateTime ;
    dct:title "Predicting the risk for dialysis or death in IgA nephropathy" ;
    dcat:accessURL <https://theses.hal.science/tel-00675243> .

<https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> a foaf:Agent ;
    foaf:name "test_moissonnage_selune" .

<https://theses.hal.science/tel-00675243> a foaf:Document .