@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix vcard: <http://www.w3.org/2006/vcard/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00669882v1> a dcat:Dataset ;
    dct:description """
              Oral clefts are congenital anomalies with a complex origin, which appears to be determined both by environmental exposures and genetic influences. The purpose of this work is to explore gene-environment interactions in their etiology. This epidemiological project is based on a case-control study, conducted in France between 1998 and 2001 (240 cases, 236 controls), which incorporates a case-parents design. Recent statistical models available for the evaluation of gene-environment interactions are described. A specific model is used to distinguish the effects of the child's and maternal genotypes. . This project focuses on ADH1C gene and maternal alcohol consumption, MTHFR gene and maternal folate intake, and maternal occupational exposure to organic solvents and genes involved in the metabolism/detoxification processes such as CYP2E1, ADH1C, GSTM1 and GSTT1.
            """ ;
    dct:identifier "tel-00669882" ;
    dct:issued "2026-05-28T19:00:09.993198"^^xsd:dateTime ;
    dct:language "fr" ;
    dct:modified "2026-05-28T19:00:09.993205"^^xsd:dateTime ;
    dct:publisher <https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> ;
    dct:title "Gene-environment interaction in oral cleft etiology" ;
    dcat:contactPoint [ a vcard:Organization ;
            vcard:fn "CCSD" ] ;
    dcat:distribution <https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00669882v1/resource/b0fa67ea-be09-413b-922e-0a99e08a2544> ;
    dcat:keyword "cas-parents",
        "cas-temoins",
        "case-control",
        "case-parent",
        "environment",
        "environnement",
        "epidemiologie",
        "epidemiology",
        "fente-orale",
        "gene",
        "infoeu-reposemanticsdoctoralthesis",
        "interaction",
        "oral-cleft",
        "sdvspeelife-sciences-q-biosante-publique-et-epidemiologie",
        "theses" ;
    dcat:landingPage <https://theses.hal.science/tel-00669882> .

<https://rec.harvest-normandie.data4citizen.com/dataset/oai-hal-tel-00669882v1/resource/b0fa67ea-be09-413b-922e-0a99e08a2544> a dcat:Distribution ;
    dct:format "HTML" ;
    dct:issued "2026-05-28T19:00:10.134789"^^xsd:dateTime ;
    dct:modified "2026-05-28T19:00:09.951756"^^xsd:dateTime ;
    dct:title "Gene-environment interaction in oral cleft etiology" ;
    dcat:accessURL <https://theses.hal.science/tel-00669882> .

<https://rec.harvest-normandie.data4citizen.com/organization/cce9db95-46d9-4dc2-84b6-764215d0a002> a foaf:Agent ;
    foaf:name "test_moissonnage_selune" .

<https://theses.hal.science/tel-00669882> a foaf:Document .